Pdf acute lung injury is a disease with high incidence of mortality and its treatment is still controversial. Ventilacion controlada por presion pcv con hipercapnia permisiva. Pac neonatologia4 libro 2 insuficiencia respiratoria neonatal. Fisiologia respiratoria, hipercapnia permisiva e injuria pulmonar. Mechanisms of action and consequences of high carbon dioxide levels. Of the infants with blood gas data, 371 32% were classi. A subset of patients is unable to tolerate lpv without significant co2 elevation. Randomized trial of oxygen saturation targets in premature infants the support trial. Permissive hypercapnia and risk for brain injury and. A trial that targeted even higher paco2 levels found that, at 18 to 22 months, children in this minimal ventilation group had. Although thought to be benign, it is becoming increasingly evident that elevated co2 levels have significant physiological effects. Fisiologia respiratoria, hipercapnia permisiva e injuria.